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AOD-9604Failed clinical evidence

GH fragment 176-191

A synthetic fragment of growth hormone's C-terminus marketed for fat loss, but with disappointing human trial results.

⚙️ How it works

Reproduces the lipolytic C-terminal domain of human GH, designed to mimic fat-breakdown signalling without GH's growth-promoting or glucose-raising actions, and does not raise IGF-1. The human receptor pathway remains poorly characterised.

🎯 What it's studied to help

Bars reflect the strength & volume of research evidence for each use — not a guarantee of results.

Strong lipolysis in obese rodents, but a 500+ person Phase 2b trial failed its primary weight-loss endpoint.

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⚠️ Educational research information only — not medical advice. Many peptides are sold strictly for laboratory research and are not approved treatments. The evidence scores reflect research interest and strength, not efficacy or safety for any individual. Always consult a qualified professional.