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TB-500Preclinical / animal evidence

Thymosin Beta-4 fragment

A synthetic fragment of Thymosin Beta-4, an actin-regulating peptide, researched for tissue repair, wound healing and regeneration.

⚙️ How it works

Sequesters G-actin to maintain a ready pool for rapid actin polymerisation, building the lamellipodia/filopodia that drive cell migration. This speeds migration of fibroblasts, keratinocytes, endothelial and stem cells to injury sites, promotes angiogenesis, upregulates laminin-5 and dampens inflammatory signalling during repair.

🎯 What it's studied to help

Bars reflect the strength & volume of research evidence for each use — not a guarantee of results.

Speeds cell migration and angiogenesis in muscle and soft-tissue repair in animal models.
Skin48/100
Increases re-epithelialisation, collagen deposition and angiogenesis in full-thickness wounds.
Promotes tenocyte/fibroblast migration and new vessel formation supporting tendon healing.
Modulates inflammatory signalling during the repair phase of healing.
Thymic origin with some immune-modulating activity, but evidence here is thin.

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⚠️ Educational research information only — not medical advice. Many peptides are sold strictly for laboratory research and are not approved treatments. The evidence scores reflect research interest and strength, not efficacy or safety for any individual. Always consult a qualified professional.