An 8-amino-acid synthetic peptide researched as an oral adjunct for celiac disease and intestinal-barrier ('leaky gut') dysfunction.
Acts as a zonulin antagonist, blocking zonulin-induced opening of intestinal tight junctions. Promotes rearrangement of tight-junction proteins and actin, tightening the epithelial barrier and reducing paracellular permeability to antigens such as gliadin.
Bars reflect the strength & volume of research evidence for each use — not a guarantee of results.
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⚠️ Educational research information only — not medical advice. Many peptides are sold strictly for laboratory research and are not approved treatments. The evidence scores reflect research interest and strength, not efficacy or safety for any individual. Always consult a qualified professional.