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SemaxClinical (Russia) evidence

Nootropic peptide

A synthetic heptapeptide derived from ACTH(4-10), researched as a nootropic and neuroprotective agent; approved in Russia for stroke recovery and cognitive disorders.

⚙️ How it works

An ACTH(4-10) analog without steroidogenic activity that rapidly upregulates BDNF and its TrkB receptor, plus NGF and VEGF, in the hippocampus and cortex, while modulating serotonergic/dopaminergic signalling — promoting neuroplasticity and neuroprotection.

🎯 What it's studied to help

Bars reflect the strength & volume of research evidence for each use — not a guarantee of results.

Upregulates BDNF/NGF and neuroplasticity supporting attention and memory; used clinically in Russia.
Modulates serotonergic/dopaminergic signalling with reported anti-anxiety/antidepressant-like effects.
Neuroprotective neurotrophic signalling is linked to resilience under cognitive stress.

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⚠️ Educational research information only — not medical advice. Many peptides are sold strictly for laboratory research and are not approved treatments. The evidence scores reflect research interest and strength, not efficacy or safety for any individual. Always consult a qualified professional.